.content-node.paragraph .content{min-height:28px}.content-node.heading .content{min-height:40px;font-weight:600;line-height:40px}.content-node.heading.level-1 .content{font-size:1.375rem}.content-node.heading.level-2 .content{font-size:1rem;font-style:italic}.content-node.heading.level-3 .content{font-size:.875rem}.content-node.list{padding:0 0 10px}.content-node .listitem{padding:2px 0 2px 20px;position:relative}.content-node .listitem .bullet{background:#bbb;width:4px;height:4px;position:absolute;top:14px;left:0}.content-node.list .content{min-height:30px}.list[class*=nested-level]{padding:0}.content-node.list.level-2 .content{font-size:1rem}.content-node.list.level-3 .content{font-size:.875rem}.content-node.list.nested-level-1{margin-left:16px}.content-node.list.nested-level-2{margin-left:32px}.content-node.list.nested-level-3{margin-left:48px}.content-node.list.nested-level-4{margin-left:64px}.content-node.list.nested-level-5{margin-left:80px}ul.simple{list-style-type:none}ul.simple li .label{float:left;white-space:nowrap;width:0;padding:0;top:0;left:-40px}.list[class*=nested-level] ul.simple li .label{left:-16px}ul ul{padding-left:0}.content-node.image .content{padding:0}.content-node.image div.image-char{width:100%}.content-node.image div.selected .overlay{background:#00a9ff40;position:absolute;inset:0}.content-node.image div img{width:100%}.content-node.codeblock>.content{color:#777;border:1px dashed #ddd;min-height:28px;padding:10px;font-family:Menlo,monospace;font-size:.875rem;line-height:20px}.lens-article .content-node.cover .content{background:0 0}.lens-article .content-node.cover .title{padding-top:20px;font-size:1.375rem;font-weight:600;line-height:1.3em}.lens-article .content-node.cover .subtitle{padding-top:10px;font-size:1rem;font-weight:600;line-height:1.3em}.lens-article .content-node.cover .label{text-align:center;margin:0 2px;padding:0 2px}.lens-article .content-node.cover .title .label{font-size:1rem;top:-.2em}.lens-article .content-node.cover .subtitle .label{font-size:.75rem}.lens-article .content-node.cover .published-on{color:#999}.lens-article .content-node.cover .published-on a{color:#999;font-weight:600}.lens-article .content-node.cover .published-on a:hover{color:#0277bd}.lens-article .content-node.cover .doi{margin-top:30px;margin-bottom:20px;font-size:.875rem}.lens-article .content-node.cover .content .authors{color:#1b6685;margin-bottom:8px;padding-top:16px;overflow:auto}.lens-article .content-node.cover .content .links{margin-top:20px;font-size:.875rem}.lens-article .content-node.cover .content .links a{margin-right:20px;padding-left:4px}.lens-article .content-node.cover .authors .text{margin:0 10px 0 0;padding:0;font-size:.875rem;display:inline-flex}.lens-article .content-node.cover .authors .text.plain{color:#777;padding-left:1px}.lens-article .intro{color:#0009;background:#fffef5;border:1px solid #d8d9c1;padding:0 10px;font-size:.8125rem;line-height:30px}.lens-article .intro .intro-text{float:left}.lens-article .intro .send-feedback{float:right;color:#e40000;font-weight:700}.lens-article .intro .send-feedback:hover{color:red}.lens-article .content-node.abstract{z-index:1;background-color:#fff}.lens-article .content-node.abstract .content{background:0 0}.lens-article .content-node.abstract .sections .content-node{word-wrap:break-word;padding-top:5px;padding-bottom:5px}.lens-article .content-node.abstract .sections ul.simple li .label{padding-top:5px}.surface.content .nodes>.content-node.supplement{padding-top:0;padding-bottom:0}.surface.content>.nodes>.content-node.supplement>.content>.label{margin-top:10px;margin-bottom:15px;font-size:1rem;font-weight:600;line-height:40px}.surface.content>.nodes>.content-node.supplement>.content .file{padding:10px 20px}.content-node.supplement .content .file{font-size:.875rem;font-weight:600}.content-node.supplement .content .file a{font-weight:600}.content-node.supplement .content .file span{padding-right:3px}.content-node.box>.content{padding:20px}.surface.content .content-node.box>.content{border:1px dotted #ddd}.surface.content .content-node.box .content{background:#fbfbfb}.surface.content .content-node.box>.content>.label{padding-bottom:20px;font-weight:600}.lens-article .resources .content-node.citation .resource-header .name{color:#888;font-size:.75rem;font-weight:400}.lens-article .content-node.citation .content .title{margin-bottom:20px;font-size:.875rem;font-weight:600}.lens-article .content-node.citation .content .authors{font-size:.875rem}.lens-article .content-node.citation .content .citation-urls .url{padding-right:20px}.lens-article .content-node.definition .description{font-size:.875rem}.resources .nodes>.content-node.figure .label{display:none}.panel.content .nodes>.content-node.figure .header{color:#777;flex-direction:row;justify-content:space-between;padding-bottom:10px;display:flex}.panel.content .nodes>.content-node.figure .header i{margin:0 8px}.panel.content .nodes>.content-node.figure .header .image-download{cursor:pointer}.panel.content .nodes>.content-node.figure>.content{border:1px solid #ddd;padding:15px}.content-node.figure div.image-wrapper{text-align:center;padding-top:20px;padding-bottom:20px}.content-node.figure div .image-wrapper img{max-width:100%;max-height:500px}.lens-article .table-caption-label{text-align:center;font-weight:700;display:block}.lens-article .content-node.html-table>.content img{width:100%}.lens-article .content-node.html-table .table-wrapper{width:100%;max-height:80vh;margin-inline:auto;height:auto!important;overflow:auto!important}.lens-article .content-node.html-table table{border-collapse:collapse;border-spacing:0;border:1px solid #d3d3d3;margin:0 auto;position:relative;font-size:.875rem!important;transform:scale(1)!important}.lens-article .content-node.html-table thead tr{background:#eee}.lens-article .content-node.html-table table sub{vertical-align:baseline;font-size:.6875rem;position:relative;top:.4em}.lens-article .content-node.html-table table td,th{vertical-align:top;border:1px solid #d3d3d3;padding:5px;font-size:.75rem}.lens-article .content-node.html-table table thead td,th{font-size:.8125rem;font-weight:700}.lens-article .content-node.html-table .footers{background:#fff;padding-top:10px;font-size:.6875rem}.resources .content-node.video .video-wrapper{text-align:center;margin-bottom:20px}.resources .content-node.video .content video{width:100%;max-height:500px}.resources .content-node.video.fullscreen .content .video-wrapper{text-align:center;padding:50px 0}.lens-article .content-node.caption .caption-title{font-size:.875rem;font-weight:600}.lens-article .content-node.caption>.content>.content-node.paragraph{padding-bottom:10px}.lens-article .resources .content-node.contributor .resource-header .name{color:#888;font-size:.75rem;font-weight:400}.surface.content .nodes>.content-node.contributor{padding-top:0;padding-bottom:0}.lens-article .content-node.contributor .affiliation{margin-top:12px;margin-bottom:12px}.lens-article .content-node.contributor .contributor-bio{padding-top:16px}.lens-article .content-node.contributor .contributor-bio .bio{font-size:.875rem}.lens-article .content-node.contributor .contributor-bio .bio .content{background:0 0}.lens-article .content-node.contributor .contributor-bio img{float:left;max-width:120px;padding-bottom:20px;padding-right:20px;display:block}.lens-article .content-node.contributor .contributor-name{margin-bottom:0;font-size:.875rem;font-weight:600}.lens-article .content-node.contributor .contrib-label{font-weight:600}.lens-article .content-node.contributor .contrib-data{margin-bottom:2px}.lens-article .content-node.contributor .contributor-name .label{margin-left:2px;margin-right:2px;padding:0 2px}.lens-article .content-node.publication-info{color:#333;font-size:.875rem}.lens-article .content-node.publication-info table{border:none;width:100%;padding:10px 0}.lens-article .content-node.publication-info .meta-data>.dates{margin-top:10px}.lens-article .content-node.publication-info .label{float:left;color:#999;width:100px;font-size:.875rem}.lens-article .content-node.publication-info .value{margin-left:140px}.article .resources .nodes>.content-node.publication-info>.content{border:none;padding:20px}.article .resources .nodes>.content-node.publication-info .content-node[data-id=articleinfo] .heading.level-3 .content{margin-top:12px;font-size:1rem}.article .resources .nodes>.content-node.publication-info .content-node[data-id=articleinfo] .content-node{padding-top:10px}.article .resources .nodes>.content-node.publication-info .content-node[data-id=articleinfo] .content-node.footnote.article-note .content-node{padding-top:0}.content-node.verse-group{padding:10px 0}.related-articles-box{background:#e3eaf1;border:1px solid #4f759c;border-radius:5px;padding:.6em 1em}.mobile .related-articles-box{margin-top:10px}.related-article .heading{align-items:center;gap:5px;font-size:1.2em;font-weight:700;display:flex}.related-article .heading i{font-size:.9em}.related-article+.related-article .heading{margin-top:.8em}.related-article .article-info{margin-top:.3em;font-size:.9em}.related-article .article-info>*{margin-top:3px}.related-article .article-info .article-title{font-size:1.1em;font-weight:700}.related-article .article-info .article-title .subtitle{font-size:.9em;font-weight:600}.related-article .article-info .article-citations{align-items:start;display:flex}.related-article a{color:#00f;text-decoration:none}.related-article .article-citations>img{width:24px;margin-right:3px}.text-with-ellipsis{text-overflow:ellipsis;-webkit-box-orient:vertical;line-height:25px;display:-webkit-box;overflow:hidden}.text-with-ellipsis.one-line{-webkit-line-clamp:1;max-height:25px}.surface,.surface .nodes,.surface .content-node{position:relative}.surface .cursor{-ms-animation:blink 1.2s step-end infinite;background:#00acea;width:2px;height:20px;-webkit-animation:1.2s step-end infinite blink;-moz-animation:1.2s step-end infinite blink;-o-animation:1.2s step-end infinite blink;animation:1.2s step-end infinite blink;position:absolute;top:0}@-webkit-keyframes blink{0%{background:#00acea}50%{background:0 0}}@-moz-keyframes blink{0%{background:#00acea}50%{background:0 0}}@-o-keyframes blink{0%{background:#00acea}50%{background:0 0}}@keyframes blink{0%{background:#00acea}50%{background:0 0}}*{-webkit-tap-highlight-color:transparent}.article{height:100%}.hidden{visibility:none}.content-node .content{margin:0}.article .document{float:left;border-right:1px solid #ddd;width:50%;height:100%;font-size:.875rem;line-height:28.5px;position:relative;overflow:hidden}.width100{width:100%!important}.article .document .surface.content{scrollbar-width:none;-ms-overflow-style:none;-webkit-overflow-scrolling:touch;position:absolute;inset:0;overflow:hidden scroll}.article .document .surface.content .nodes{background:#fff;min-height:100%;padding-bottom:50px;padding-left:20px;padding-right:0}.article .panel.hidden{visibility:hidden}.menu-bar{color:#444;z-index:20000;border-bottom:1px solid #ddd;height:40px;position:absolute;top:0;left:0;right:0;overflow:hidden}.menu-bar .context-toggles a{float:left;color:#0006;border-right:1px solid #ddd;padding-left:15px;padding-right:15px;font-size:.8125rem;font-weight:600;line-height:40px;display:block}.menu-bar .context-toggles a.context-toggle.hidden{display:none}.menu-bar .context-toggles a:hover{color:#00000080;background:#00000008}.menu-bar .context-toggles a.active{color:#444;background:#0000000d;border-bottom:3px solid #444}@media (width<=1500px){.menu-bar .context-toggles:not(.external-menu) a{text-align:center;width:48px;padding-top:4px;font-size:0}.menu-bar .context-toggles:not(.external-menu) a>.fa{font-size:.8125rem}}.article .resources{float:right;width:50%;height:100%;padding-left:50px;padding-right:50px;line-height:25px;position:relative}.article .resources .panel{position:absolute;inset:40px 0 0}.article .resources .surface{-webkit-overflow-scrolling:touch;position:absolute;inset:0;overflow:hidden scroll}.article .nodes{padding-left:50px;padding-right:50px}.article .resources .nodes{padding-left:0;padding-right:20px}.article .resources .nodes>.content-node{background:#fff;border-bottom:1px solid #ddd;border-left:3px solid #0000;padding:0;position:relative}.article .resources .nodes>.content-node.publication-info{border-bottom:unset}.article .resources .nodes>.content-node>.content{border-top:none}.article .resources .nodes>.content-node.contributor>.content{padding-bottom:8px}.article .contrib-data img.orcid{vertical-align:middle;width:1.2em;margin-right:8px;display:inline-block}.article .contrib-data a.orcid{vertical-align:middle}.article .resources .nodes>.content-node[data-id$=author_list].heading.level-3>.content{font-size:1rem}.article .resources .content-node .resource-header{padding-top:15px;font-weight:600;position:relative}.article .resources .content-node.contributor .resource-header div{display:none}.article .resources .panel .toc{z-index:1;background:#fff;padding:16px 20px 30px;position:absolute;inset:0;overflow:auto}.article .resources .resource-header .name{min-height:30px;padding:0 200px 0 20px;font-size:1rem;line-height:21px;display:block}.article .resources .content-node .reference-count{text-align:right;font-size:.8125rem;position:absolute;top:40px;right:20px}.article .resources .content-node .resource-header .toggles{position:absolute;top:0;right:0;overflow:auto}.article .resources .content-node .resource-header .toggle{float:left;text-align:center;color:#0006;padding:0 20px;font-size:.75rem;font-weight:600;line-height:50px;bottom:0}.article .resources .content-node .resource-header .toggle.image-download{cursor:pointer}.article .resources .content-node .resource-header .toggle i{padding-right:5px}.article .resources .figures .content-node.highlighted .resource-header .toggle.toggle-res,.article .resources .math .content-node.highlighted .resource-header .toggle.toggle-res{color:#91bb04}.article .resources .citations .content-node.highlighted .resource-header .toggle.toggle-res{color:#0b9dd9}.article .resources .info .content-node.highlighted .resource-header .toggle.toggle-res{color:#5c6570}.article .resources .content-node .resource-header .toggle:hover{color:#0009}#container .article .content-node.highlighted .fa.fa-eye-slash{display:inline}.article .resources .content-node .findnext_control,.article .resources .content-node .hide_control,.article .resources .content-node.highlighted .find_control{display:none}.article .resources .content-node.highlighted_next .findnext_control{display:inline}.article .resources .content-node.highlighted_last .findnext_control{display:none}.article .resources .content-node.highlighted_last .hide_control{display:inline}.article .resources .figures .content-node.fullscreen .resource-header .toggle.toggle-fullscreen,.article .resources .math .content-node.fullscreen .resource-header .toggle.toggle-fullscreen{color:#91bb04}#container .article .content-node.fullscreen{z-index:100000;-webkit-overflow-scrolling:touch;margin-bottom:0;margin-right:0;padding:0;position:fixed;inset:0}#container .article .content-node.fullscreen>.content{position:absolute;inset:80px 0 0;overflow:auto}#container .article .surface.info .content-node.caption .content{padding:20px}span.annotation.sc{font-variant:small-caps}span.annotation.formula_reference,span.publication_reference{padding-left:3px;padding-right:3px}.article span.emphasis,.article em{font-style:italic}.article span.superscript,.article sup{vertical-align:super;font-size:.75rem}.article span.subscript,.article sub{vertical-align:sub;font-size:.75rem}.article .cover span.superscript,.article .cover span.subscript,.article .cover sup,.article .cover sub{font-size:inherit}.article span.strong,.article strong{font-weight:700}.article span.underline{text-decoration:underline}.article span.label{vertical-align:baseline;padding:5px;font-size:.75rem;font-weight:700;position:relative;top:-.4em}.article .emails.contrib-data span span{margin-right:5px}.content-node .idea{background-color:#66b6204d}.content-node .question{background-color:#10a7de4d}.content-node .error{background-color:#ed60304d}.content-node .link{font-weight:700}.content-node .link:hover,.content-node .link.highlighted{color:#0b9dd9}.content-node .code{-webkit-font-smoothing:subpixel-antialiased;background:#eee;padding:2px 3px;font-family:Consolas,Liberation Mono,Courier,monospace;font-size:.8125rem}.content-node .idea.highlight{background-color:#66b62099}.content-node .question.highlight{background-color:#10a7de99}.content-node .error.highlight{background-color:#ed603099}.content-node .content span.selected{background:#00000014}.content-node .content .idea.selected{background-color:#66b62066}.content-node .content .question.selected{background-color:#10a7de66}.content-node .content .error.selected{background-color:#ed603066}.content-node .emphasis{font-style:italic}.content-node .strong{font-weight:700}.content-node .figure_reference{color:#495a11;cursor:pointer;background:#91bb0426;border-bottom:1px solid #91bb0499}.content-node .contributor_reference{cursor:pointer;padding:2px 1px}.content-node .citation_reference{color:#1b6685;cursor:pointer;background:#0b9dd913;border-bottom:1px solid #0b9dd966;padding-left:3px;padding-right:3px}.content-node .cross_reference{cursor:pointer;background:#0000000d;border-bottom:1px solid #00000040}.content-node .definition_reference{cursor:pointer;background:#0000000d;border-bottom:1px solid #00000040;font-style:italic}.content-node.citation .link{word-break:break-all}.content-node .figure_reference:hover{background-color:#91bb0459}.content-node .citation_reference:hover{background-color:#0b9dd94d}.content-node .contributor_reference:hover{background-color:#0000000d}.content-node .definition_reference:hover{background-color:#0000001a}.content-node .figure_reference.highlighted{background:#91bb04b3}.content-node .citation_reference.highlighted{background:#0b9dd999}.content-node .contributor_reference.highlighted,.content-node .definition_reference.highlighted{color:#fff;background-color:#5c6570}.content-node .figure_reference.highlighted_current{background:#91e604}.content-node .citation_reference.highlighted_current{background:#0b9dd9}.content-node .cross_reference:hover{background-color:#0000001a}.surface.content .nodes>.content-node{word-wrap:break-word;padding:6px 16px}.surface.content .nodes>.content-node.cover{padding-top:16px!important}.surface.content .nodes>.content-node.quote{padding-left:80px}.resources .content-node.image div img,.resources .content-node.paragraph .content-node.image div img{width:auto}.resources .nodes>.content-node>.content{padding:0 20px 20px}.resources .info .nodes>.content-node.paragraph>.content>.content-node{padding:20px 0}.article .document .surface.content::-webkit-scrollbar{width:0;height:0}.article .document .surface.content::-webkit-scrollbar-thumb{background-color:#0000}.article .resources .panel::-webkit-scrollbar,.article .resources .surface::-webkit-scrollbar{width:0;height:0}.article .resources .panel::-webkit-scrollbar-thumb,.article .resources .surface::-webkit-scrollbar-thumb{background-color:#0000}.surface-scrollbar .overlay{z-index:3000}.resources .surface-scrollbar{position:absolute;inset:0 0 0 auto}#container.touchable .resources .surface-scrollbar{right:5px}#container.touchable .toggle-fullscreen{display:none}#container.touchable .article .document .surface.content{right:20px}#container.touchable.ios .surface-scrollbar .visible-area{display:none}#container.touchable .surface-scrollbar .node:hover{opacity:.15}#container.touchable .surface-scrollbar .arrow,.content-node.heading .top{display:none}.article .resources .figures .content-node.highlighted{border-left:3px solid #91bb04}.article .resources .citations .content-node.highlighted{border-left:3px solid #0b9dd9}.article .resources .definitions .content-node.highlighted,.article .resources .info .content-node.highlighted{border-left:3px solid #5c6570}.resource-view.toc .heading-ref{cursor:pointer;color:#000c;border:1px solid #0000;margin-right:10px;padding:4px 10px;font-size:1rem;font-weight:600;line-height:20px;display:block}.resource-view.toc .heading-ref .label{padding-right:10px;display:inline}.resource-view.toc .heading-ref.active{color:#000000e6;background:#fff;border:1px solid #eee}.resource-view.toc .heading-ref.level-2{padding-left:20px;font-size:.875rem}.resource-view.toc .heading-ref.level-3{padding-left:40px;font-size:.875rem}.resource-view.toc .heading-ref.level-4{padding-left:60px;font-size:.875rem}.resource-view.toc .heading-ref.level-5{font-size:.875rem}.resource-view.toc .heading-ref:hover{color:#000}.surface-scrollbar{background:#eee;width:20px;position:absolute;top:0;bottom:0;left:0}.surface-scrollbar .node.overlay{min-height:2px;position:absolute}.surface-scrollbar .visible-area{z-index:4000;background-color:#0003;height:80px;position:absolute;top:40px;left:0;right:0}.surface-scrollbar.hidden .visible-area{display:none}.surface-scrollbar:hover .visible-area{background-color:#00000040}.surface-scrollbar .visible-area:hover{background-color:#0000004d}.surface-scrollbar .node{width:20px;margin:0}.node.highlighted{background:#5c6570}.article .resources .figures .surface-scrollbar .highlighted,.article .content .surface-scrollbar .highlighted.figure_reference,.article .content .surface-scrollbar .highlighted.figure{background-color:#91bb04}.article .content .surface-scrollbar .highlighted.figure.main-occurrence{border-right:3px solid #5c6148}.article .resources .citations .surface-scrollbar .highlighted,.article .content .surface-scrollbar .highlighted.citation_reference{background-color:#0b9dd9}.article .resources .definitions .surface-scrollbar .highlighted,.article .content .surface-scrollbar .highlighted.definition_reference{background-color:#5c6570}.panel.document .nodes>.content-node>.focus-handle{cursor:pointer;background:#fff;border-left:3px solid #ccc;width:30px;display:none;position:absolute;top:0;bottom:2px;left:0}.panel.document .nodes>.content-node>.focus-handle:hover{border-left:3px solid #bbb}.content-node.footnote{border:1px solid #ddd;border-radius:5px;margin:20px 0;padding:20px;font-size:.8125rem;display:block!important}.surface.content .nodes>.content-node.footnote,.article .resources .nodes>.content-node.footnote{font-size:unset;border:none;margin:4px 0 0}.surface.content .nodes>.content-node.footnote{padding-top:0;padding-bottom:0}.surface.content .nodes>.content-node.footnote+.content-node.footnote,.article .resources .nodes>.content-node.footnote+.content-node.footnote{margin-top:0}.footnote-reference>a{vertical-align:super;border:1px solid #ddd;padding:0 2px;font-size:.8125rem}.footnote-reference>a:hover{background:#eee}.footnote-reference.sm-expanded>a{background:#ddd}.footnote-reference>.footnote{display:none!important}.footnote-reference.sm-expanded>.footnote{display:block!important}.content-node.footnote.article-note{border:unset;margin:20px 0 0;padding:0;font-size:.875rem}.surface .content-node.footnote.author-note>.content.author-note{padding-bottom:0}.surface .content-node.footnote.author-note:last-child>.content.author-note{padding-bottom:20px}.content-node.footnote>.content.author-note>span.label{float:left;padding:0 5px}.content-node.footnote>.content.article-note>span.label{float:left;width:auto;padding:0 5px}.content-node.footnote .content.article-note .content-node{padding:0}#MathJax_Message{display:none!important}*{margin:0}body{background-color:#fff;margin:0;padding:0}html{-webkit-font-smoothing:antialiased;height:100%}body.reader{height:100%;position:fixed;inset:0;overflow:hidden}.container:after{content:"";clear:both;display:block}#container{min-width:800px;margin:0 auto;position:relative}body.reader #container{height:100%}body,textarea,p,input{color:#505050;font-family:opensans-regular,Source Sans Pro,Helvetica,Arial,Verdana,sans-serif}a{color:#1b6685;font-weight:400;text-decoration:none}a:hover{color:#0b9dd9}img{border:none;margin:0;padding:0}strong,h1,h2,h3{font-weight:700}h1 a,h1 a:hover{color:#fff}h2{padding-bottom:20px;font-size:1.75em}h3,h4,h5,h6{margin-bottom:20px;font-size:1em;font-weight:700}p{padding-bottom:20px}p:last-child{padding-bottom:0}.small{color:#505050;font-size:.75em;font-weight:400}*{-webkit-box-sizing:border-box;-moz-box-sizing:border-box;box-sizing:border-box}#container .article .resources .info .content-node.active .resource-header{background:#5c6570}.article .resources .nodes>#articleinfo>.content{border-top:1px solid #ddd}.article span.annotation.author-callout-style1{color:#b70e0e;font-weight:700}.article span.annotation.author-callout-style2{color:#00b3ff;font-weight:700}.article span.annotation.author-callout-style3{color:#04c304;font-weight:700}.article span.annotation.author-callout-style4{color:gold;font-weight:700}#main{position:relative}body.reader #main{height:100%}#container .loading{height:49px;font-size:.75rem;line-height:50px;position:absolute;top:15px;left:70px;right:0}.spinner-wrapper{z-index:5000;width:150px;margin-left:-75px;display:none;position:fixed;top:40%;left:50%}body.loading .spinner-wrapper{display:block}.spinner-wrapper .spinner{background:#444;width:40px;height:40px;margin:0 auto;-webkit-animation:1.2s ease-in-out infinite rotateplane;animation:1.2s ease-in-out infinite rotateplane}.spinner-wrapper .message{color:#444;text-align:center;padding-top:20px;font-size:.75rem}@-webkit-keyframes rotateplane{0%{-webkit-transform:perspective(120px)}50%{-webkit-transform:perspective(120px)rotateY(180deg)}to{-webkit-transform:perspective(120px)rotateY(180deg)rotateX(180deg)}}@keyframes rotateplane{0%{-webkit-transform:perspective(120px)rotateX(0)rotateY(0);transform:perspective(120px)rotateX(0)rotateY(0)}50%{-webkit-transform:perspective(120px)rotateX(-180.1deg)rotateY(0);transform:perspective(120px)rotateX(-180.1deg)rotateY(0)}to{-webkit-transform:perspective(120px)rotateX(-180deg)rotateY(-179.9deg);transform:perspective(120px)rotateX(-180deg)rotateY(-179.9deg)}}.caption .sm-expanded .footnote{position:relative}.sm-expanded .footnote{background:#d3d3d3;margin:0;padding:10px;position:absolute;left:0;right:0}.footnote-reference a{border:none;padding-left:0}.document .content-node.figure-group>.content{border:1px solid #ddd;padding:15px}.content-node.figure-group .caption .caption-title{color:#777}.resources .content-node.figure-group>.content{padding:15px}.fullscreen .action-toggle-resource{display:none}.document .content-node.formula{text-align:center;min-height:80px;padding:30px 60px 30px 100px}.document .content-node.formula .label{line-height:40px;position:absolute;top:0;bottom:0;right:50px}.document .content-node .MathJax_Display{margin:0;padding:20px;overflow:auto}.document .content-node.formula .MathJax_Preview img{width:80%}.textual_annotation:after{content:" "}.back{cursor:pointer}.pubmed{margin-left:8px}.pubmed a{font-weight:700}.googlescholar{margin-left:8px}.googlescholar a{font-weight:700}.jbjs{margin-left:8px}.jbjs a{font-weight:700}.lens-article .content-node.html-table .caption{text-align:center}.lens-article .content-node.html-table table{border-style:solid}.lens-article .content-node.html-table table caption{text-align:left}.lens-article .content-node.html-table .footers .footer{line-height:.875rem}.lens-article .content-node.html-table .table-caption-label{padding-right:16px}.surface.content>.nodes>.content-node.videosummary>.content>.label{margin-top:5px;margin-bottom:5px;font-size:1rem;font-weight:600;line-height:40px}.article>.resources>.panel.hidden .video-js{display:none}.lens-article .content-node.affiliation .label{color:#888;font-size:.75rem;font-weight:400}.article .nodes>.content-node.affiliation:last-child{padding-bottom:20px}.article .nodes>.content-node.affiliation>.content{padding-bottom:0}.article .nodes>.content-node.affiliation{border-bottom:none;padding-top:0;padding-bottom:0}.surface.supplemental>.nodes>.content-node>.content>.infographic-wrapper>.viewer>.pages{height:500px}.surface.content>.nodes>.content-node>.content>.infographic-wrapper>.viewer>.pages{height:300px;overflow:auto}.content-node.infographic>.content>.label{margin-right:40px;display:inline-block}.surface.content>.nodes>.content-node.infographic>.content>.label{margin-top:5px;margin-bottom:5px;font-size:1rem;font-weight:600;line-height:40px}.content-node.infographic>.content>.link{display:inline-block}.viewer{text-align:center;position:relative!important}.viewer>.progress-bar{background-color:#00f;width:0%;height:8px;top:0;left:0;position:absolute!important}.viewer>.pages{text-align:center;cursor:-webkit-grab;cursor:-moz-grab;cursor:-o-grab;cursor:grab;background-color:gray;padding:16px 16px 0;overflow:hidden}.viewer>.pages:active{cursor:-webkit-grabbing;cursor:-moz-grabbing;cursor:-o-grabbing;cursor:grabbing}.viewer.full-screen>.pages{height:100%!important}.viewer>.pages>.page{margin-bottom:16px;box-shadow:0 0 4px 3px}.viewer>.toolbar{width:100%;bottom:0;position:absolute!important}.viewer>.toolbar>button{background-color:#fff;border:1px solid #505050;border-radius:16px;min-width:32px;height:32px;margin:8px;box-shadow:0 0 4px}.full-screen{width:100%!important;height:100%!important}.full-screen-pseudo{overflow:hidden!important}.full-screen-pseudo .full-screen{z-index:9999999;inset:0;position:fixed!important}.infographic_reference{display:none}.videosummary_reference{display:none}video{max-height:unset!important}.vjs-playlist img{float:left;width:40%}.vjs-playlist-title-container{width:100%}.vjs-playlist-name{text-align:right;width:100%}.authorinsights_reference,.supplement_reference{display:none}.surface.content .nodes>.content-node.eletter{padding-top:0;padding-bottom:0}.content-node.eletter>.content{padding:10px 20px}.content-node.eletter .content .file{font-size:1rem;font-weight:600}.content-node.eletter .content .file a{font-weight:600}.content-node.eletter .content .file span{padding-right:3px}.surface.content .nodes>.content-node.eletter-submit{padding-top:0;padding-bottom:0;display:none!important}.surface.content>.nodes>.content-node.eletter-submit>.content .link{padding:0 20px}.content-node.eletter-submit>.content .link{position:relative!important}.surface.content>.nodes>.content-node.eletter-submit>.content>.label{margin-top:10px;margin-bottom:15px;font-size:1rem;font-weight:600;line-height:40px}.content-node.eletter-submit>.content a>.label{font-size:.875rem;position:absolute;top:50%;transform:translateY(-50%)}.eletter_reference{display:none}.menu-bar .context-toggles.external-menu{float:right;border-left:1px solid #ddd}.menu-bar .context-toggles.external-menu a{color:#1b6685}.surface.supplemental>.nodes>.content-node>.content{padding-top:20px}.highlight{background-color:orange;transition:background-color .5s ease-in-out}.image-download,.videosummary{display:none}